Tyrosine Hydroxyl Lone Pair: Crucial For Tyrosinase Catalysis
Tyrosine hydroxyl lone pair is a crucial entity in the catalytic mechanism of tyrosinase, interacting closely with its copper ions. This lone pair participates in the oxidation of substrates by donating electrons to the substrate, forming a phenolate radical intermediate. The lone pair’s reactivity is influenced by various factors, including the protein environment surrounding the … Read more